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Per the brand's disclosed exclusion criteria, the protocol is not appropriate for anyone with active cancer or a personal history of hormone-sensitive cancer, pituitary tumors or disease, uncontrolled diabetes or active diabetic retinopathy, severe kidney or liver disease, active cardiovascular disease or a recent cardiac event, pregnancy or breastfeeding, a known allergy to either compound, or anyone under 18

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Nrf2 transcriptionally activates GGT [29], which plays a key role in glutathione homeostasis by breaking down extracellular glutathione into its constituent parts, which can be taken up by the cell for intracellular glutathione synthesis [30]