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These findings underscore the developmental importance of early microbial signals in shaping neural circuits and behavior, processes modulated by molecules such as reelin, which controls dendritic growth and synaptic receptor function in post-natal entorhinal cortex neurons (Hamad et al., 2021b,a, 2024b,a

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Challenges and Future Directions One of the major challenges in translating microbiome- and nutrition-based interventions into clinical practice is the need for strain- and nutrient-specific recommendations