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Throughout the Western world, celiac disease has a prevalence of ∼1%, affecting ∼3 million people within the United States alone, where it reportedly has a diagnosis rate of only 15% (2–4)

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In vitro / cell culture Fibroblast migration, F-actin, FAK–paxillin, growth hormone receptor expressionExtensive Animal models — chiefly rat Transected Achilles tendon, gastrointestinal injury, vascular and neurological modelsExtensive Human clinical data Three pilot studies in total, per a 2025 review of the musculoskeletal literatureMinimal Large randomised controlled trials in humans None FDA approval Not approved for use in standard medicine by FDA or other regulatorsNone WADA status 2026 Prohibited List, S0 — named explicitly