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Détoxification hépatique : conjugaison phase II Dans le foie, le glutathion est un acteur central de la détoxification phase II : les enzymes glutathion-S-transférases (GST) conjuguent le glutathion à des molécules toxiques lipophiles — médicaments, polluants, métaux lourds, métabolites cancérigènes — pour les rendre hydrosolubles et éliminables via la bile ou les urines