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Cycle Length: Research protocols vary, but use is generally suggested for 3-5 days weekly or continuously for 4-8 weeks to achieve normalization of sleep architecture

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The randomized, placebo- controlled IFIGENIA trial in 182 patients with IPF investigated the effectiveness of 1-year treatment with high-dose oral NAC (600 mg, three times daily) added to standard therapy with prednisone plus azathioprine [29]