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En un estudio clínico multicéntrico europeo, la suplementación con L-carnitina (en forma de propionil-L-carnitina a 2 g/día durante 12 meses) en pacientes con claudicación moderada a severa relacionada con la distancia máxima recorrida y la calidad de vida percibida logró una mejora significativa en comparación con los pacientes que solo recibieron placebos

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