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Cagrilintide is an amylin analogue that helps regulate appetite. In a randomized trial of over 3400 patients who were overweight or obese and had ≥1 weight-related complication, individuals assigned to a combination

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Novo Nordisk built CagriSema (semaglutide + cagrilintide) to dethrone tirzepatide, Lilly's drug, from the top of the weight-loss market. On 2/23/26, phase 3 came in at 23.0% weight loss vs. 25.5% for

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